Optimization of Cr content of metastable β-type Ti-Cr alloys with changeable Youngs modulus for spinal fixation applications

Xingfeng Zhao, Mitsuo Niinomi, Masaaki Nakai, Junko Hieda, Takuya Ishimoto, Takayoshi Nakano

Research output: Contribution to journalArticlepeer-review

80 Citations (Scopus)

Abstract

Metallic implant rods used in spinal fixtures should have a Youngs modulus that is sufficiently low to prevent stress shielding for the patient and sufficiently high to suppress springback for the surgeon. Therefore, we propose a new concept: novel biomedical titanium alloys with a changeable Youngs modulus via deformation-induced ω phase transformation. In this study, the Cr content in the range of 10-14 mass% was optimized to produce deformation-induced ω phase transformation, resulting in a large increase in the Youngs modulus of binary Ti-Cr alloys. The springback and cytotoxicity of the optimized alloys were also examined. Ti-(10-12)Cr alloys exhibit an increase in Youngs modulus owing to deformation-induced ω phase transformation. In this case, such deformation-induced ω phase transformation occurs along with {3 3 2} β mechanical twinning, resulting in the maintenance of acceptable ductility with relatively high strength. Among the examined alloys, the lowest Youngs modulus and largest increase in Youngs modulus are obtained from the Ti-12Cr alloy. This alloy exhibits smaller springback than and comparable cytocompatibility to the biomedical Ti alloy Ti-29Nb-13Ta-4.6Zr.

Original languageEnglish
Pages (from-to)2392-2400
Number of pages9
JournalActa Biomaterialia
Volume8
Issue number6
DOIs
Publication statusPublished - 2012 Jul

Keywords

  • Biomaterials
  • Changeable Youngs modulus
  • Cytocompatibility
  • Deformation-induced ω phase
  • β-type Ti-Cr alloys

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Biochemistry
  • Biomedical Engineering
  • Molecular Biology

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