Optimal conditions for tissue perforation using high intensity focused ultrasound

Takashi Mochizuki, Taizo Kihara, Kouji Ogawa, Ryoko Tanabe, Shin Yosizawa, Shin Ichiro Umemura, Takashi Kakimoto, Hiromasa Yamashita, Toshio Chiba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To perforate tissue lying deep part in body, a large size transducer was assembled by combining four spherical-shaped transducers, and the optimal conditions for tissue perforation have studied using ventricle muscle of chicken as a target. The ex vivo experiments showed that ventricle muscle was successfully perforated both when it was exposed to High Intensity Focused Ultrasound (HIFU) directly and when it was exposed to HIFU through atrial muscle layer. Moreover, it was shown that calculated acoustic power distributions are well similar to the perforation patterns, and that the acoustic energy distributes very complexly near the focus. Lastly, perforation on the living rabbit bladder wall was demonstrated as a preliminary in vivo experiment.

Original languageEnglish
Title of host publication11th International Symposium on Therapeutic Ultrasound
Pages245-249
Number of pages5
DOIs
Publication statusPublished - 2012 Dec 1
Event11th International Symposium on Therapeutic Ultrasound, ISTU 2011 - New York, NY, United States
Duration: 2011 Apr 112011 Apr 13

Publication series

NameAIP Conference Proceedings
Volume1481
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other11th International Symposium on Therapeutic Ultrasound, ISTU 2011
CountryUnited States
CityNew York, NY
Period11/4/1111/4/13

Keywords

  • HIFU
  • non-invasive tissue ablation
  • therapeutic ultrasound

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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