Optical resolution of aromatic alcohols using silica nanoparticles grafted with helicene

Wataru Ichinose, Masamichi Miyagawa, Zengjian An, Masahiko Yamaguchi

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Optically active silica nanoparticles, with a 70-nm diameter, grafted with (P)-1,12-dimethyl-8-methoxycarbonylbenzo[c]phenanthrene-5-carboxyamide were synthesized, and their use in the kinetic resolution of aromatic alcohols was examined. Up to 61% ee for (S)-2,2-dimethyl-1-phenyl-1-propanol was obtained by a preferential precipitation of aggregates formed with (P)-nanoparticles.

Original languageEnglish
Pages (from-to)3123-3125
Number of pages3
JournalOrganic letters
Volume14
Issue number12
DOIs
Publication statusPublished - 2012 Jun 15

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Optical resolution of aromatic alcohols using silica nanoparticles grafted with helicene'. Together they form a unique fingerprint.

Cite this