Ontogeny of cholinergic ganglionic cells which take up L-3,4-dihydroxyphenylalanine and contain vasoactive intestinal polypeptide in the mouse tongue

Hiroyuki Ichikawa, S. Matsuo, S. Wakisaka, M. Akai

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

During the prenatal development of the mouse tongue, the intralingual ganglion was investigated histo-chemically and immunohistochemically for acelylcholineslerase (AChE) activity, the capacity to take up L.-3.4-dihy-droxyphenylalaninc (L-DOPA) and vasoactive intestinal polypcptidc (VlP)-Hkc immunorcactivity. Ache-positive cells were first observed at gestational day 12, and Ache-positive neurons which take up L-DOPA were found at gestational day 14. while VIP-like immunoreactive neurons were not seen until gestational day 16. The present results suggested that the cholinergic neurons within the mouse tongue can take up /.-DOPA from gestational day 14 and synthesize VIP from gcstalional day 16.

Original languageEnglish
Pages (from-to)135-138
Number of pages4
JournalCells Tissues Organs
Volume140
Issue number2
DOIs
Publication statusPublished - 1991

Keywords

  • Acetylcholinesterase
  • Intralingual ganglion
  • L-3,4-Dihydroxyphenylalanine
  • Ontogeny
  • Vasoactive intestinal polypeptide

ASJC Scopus subject areas

  • Anatomy
  • Histology

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