On-chip temperature sensing and control for cell immobilization

Ikusei Rin, Yoko Yamanishi, Fumihito Arai

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    22 Citations (Scopus)

    Abstract

    In this study, a temperature sensing and controlling microfluid chip has been developed for cell immobilization using a thermo-sensitive hydrogel (PNIPAAm). The PDMS-based micromagnetic stirrers make microscale fluid mixing to provide the temperature stability in the microchannel. The ITO (Indium Tin Oxide) microheaters and thermosensors, fabricated by micromachining technology, perform in situ fluid heating and feedback temperature control. All temperature sensing and controlling devices are integrated on a chip, in which yeast cell immobilization is performed by the gelation of the PNIPAAm solution.

    Original languageEnglish
    Title of host publicationProceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
    Pages659-663
    Number of pages5
    DOIs
    Publication statusPublished - 2007 Aug 28
    Event2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 - Bangkok, Thailand
    Duration: 2007 Jan 162007 Jan 19

    Publication series

    NameProceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007

    Other

    Other2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
    CountryThailand
    CityBangkok
    Period07/1/1607/1/19

    Keywords

    • Cell immobilization
    • ITO
    • PDMS
    • Stirrer
    • Temperature

    ASJC Scopus subject areas

    • Computer Networks and Communications
    • Computer Science Applications
    • Electrical and Electronic Engineering

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