Observation of in Vitro Activities and clinical Evaluation Infection on KW-1062

Akira Watanabe, Masako Sasaki, Yukinori Yonemoto, Sonoko Saito, Kotaro Oizumi, Kiyoshi Konno

    Research output: Contribution to journalArticlepeer-review


    In vitro antimicrobial activity and therapeutic effects of KW-1062 on respiratory tract infections were evaluated and the following results were obtained. The MICs of the drug against clinical isolates of Klebsiella pneumoniae were slightly lower than those of DKB and nearly the same as those of GM. The drug was revealed to be less effective than GM or DKB against Pseudomonas aeruginosa. Of 4 cases, treated with the drug, of respiratory tract infections with gram negative bacilli, an excellent bacteriological and clinical effect was observed in one case, but the 3 remaining cases showed negative clinical responses during the periods of the administration of the drug.

    Original languageEnglish
    Pages (from-to)1934-1938
    Number of pages5
    Issue number7
    Publication statusPublished - 1977 Jan 1

    ASJC Scopus subject areas

    • Pharmacology (medical)
    • Infectious Diseases
    • Pharmacology
    • Drug Discovery
    • Oncology


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