Mesh generation is one of the critical problems in numerical simulation of cascade flow, particularly cooled turbine blade. To overcome this problem, Cartesian-mesh CFD solver is focused these days. In this study, block-structured Cartesian-mesh solver, Building-Cube Method (BCM), is applied to cascade flow of T106 low pressure turbine cascade. Ghost-cell approach is employed to represent the curved surface of T106 blade. The result is compared with the result of wall boundary condition with staircase representation. As a result, Ghost-cell approach can mitigate the pressure oscillations and obtain more smooth results. The computational results are also compared with experimental results for the validation, and the similar surface pressure coefficients are obtained. However, the difference is observed at the location of laminar-turbulent transition due to the lack of mesh resolution.