Numerical analysis of flow pattern and mass transfer around an axisymmetric red blood cell moving in a fine capillary

Atsushi Shirai, Satoyuki Kawano, Hiroyuki Hashimoto, Shinichi Nitta

Research output: Contribution to journalArticlepeer-review

Abstract

To analyze the flow field and the mass transfer characteristics around a red blood cell moving in a fine capillary, we developed a code for grid generation around the arbitrary body and a numerical code to solve the axisymmetric Navier-Stokes equations and the diffusion equation. The numerical code was developed based on the finite difference technique and the curvilinear coordinate transformation technique. In the present paper, a red blood cell was approximated to be an axisymmetric parachute configuration based on the experimental observations. The flow field and the mass transfer characteristics around a red blood cell moving under the zero drag condition in a fine capillary were numerically obtained. Consequently, it was found that there existed an attached wake behind the red blood cell in parachute configuration even at extremely low Reynolds numbers of 0.001, and that the pressure and the shear stress along the membrane of red blood cell changed steeply. It was also found that the velocity or the physical properties of the plasma and the diffusion coefficient of the oxygen had little effect on mean Sherwood number at extremely low Reynolds numbers of 0.001 and in the range of Pe≤10.

Original languageEnglish
Pages (from-to)151-160
Number of pages10
Journaljapanese journal of medical electronics and biological engineering
Volume34
Issue number2
Publication statusPublished - 1996 Jul 30

ASJC Scopus subject areas

  • Biomedical Engineering

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