Nucleophilic aromatic substitution reactions of 1-methoxy-2- (diphenylphosphinyl)naphthalene with C-, N-, and O-nucleophiles: Facile synthesis of diphenyl(1-substituted-2-naphthyl)phosphines

T. Hattori, J. Sakamoto, N. Hayashizaka, S. Miyano

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

A novel nucleophilic aromatic substitution reaction is described in which the methoxy group of 1-methoxy-2-(diphenylphosphinyl)-naphthalene is readily replaced with Grignard reagents, alkoxides, and amides. Reduction of the resulting phosphine oxides provides a convenient route to diphenyl(1- substituted-2-naphthyl)phosphines.

Original languageEnglish
Pages (from-to)199-202
Number of pages4
JournalSynthesis
Issue number2
DOIs
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Nucleophilic aromatic substitution reactions of 1-methoxy-2- (diphenylphosphinyl)naphthalene with C-, N-, and O-nucleophiles: Facile synthesis of diphenyl(1-substituted-2-naphthyl)phosphines'. Together they form a unique fingerprint.

  • Cite this