2-Alkylsulfonyl, -phenoxysulfonyl or -sulfamoyl substituted 1-methoxynaphthalenes 1 undergo nucleophilic displacement of the 1-methoxy group when treated with Grignard reagents; the chiral sulfamoyl-substituted naphthalene 1f on treatment with the 2-methoxy-1-naphthyl Grignard reagent 2d induced axial chirality to give the 1,1′-binaphthyl 3fd in 80% diastereoisomeric excess (de).
|Number of pages||2|
|Journal||Journal of the Chemical Society, Perkin Transactions 1|
|Publication status||Published - 1995|
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