TY - JOUR
T1 - Nucleophilic aromatic substitution of 2-sulfonyl-substituted 1-methoxynaphthalenes with Grignard reagents
AU - Hattori, Tetsutaro
AU - Suzuki, Mikio
AU - Komuro, Yasuko
AU - Miyano, Sotaro
PY - 1995
Y1 - 1995
N2 - 2-Alkylsulfonyl, -phenoxysulfonyl or -sulfamoyl substituted 1-methoxynaphthalenes 1 undergo nucleophilic displacement of the 1-methoxy group when treated with Grignard reagents; the chiral sulfamoyl-substituted naphthalene 1f on treatment with the 2-methoxy-1-naphthyl Grignard reagent 2d induced axial chirality to give the 1,1′-binaphthyl 3fd in 80% diastereoisomeric excess (de).
AB - 2-Alkylsulfonyl, -phenoxysulfonyl or -sulfamoyl substituted 1-methoxynaphthalenes 1 undergo nucleophilic displacement of the 1-methoxy group when treated with Grignard reagents; the chiral sulfamoyl-substituted naphthalene 1f on treatment with the 2-methoxy-1-naphthyl Grignard reagent 2d induced axial chirality to give the 1,1′-binaphthyl 3fd in 80% diastereoisomeric excess (de).
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U2 - 10.1039/p19950001473
DO - 10.1039/p19950001473
M3 - Article
AN - SCOPUS:37049084943
SN - 1470-4358
SP - 1473
EP - 1474
JO - Journal of the Chemical Society. Perkin Transactions 1
JF - Journal of the Chemical Society. Perkin Transactions 1
IS - 12
ER -