TY - JOUR
T1 - Novel Cytocidal Compounds, Oxopropalines From Streptomyces Sp. G324 Producing Lavendamycin I. Taxonomy of the Producing Organism, Fermentation, Isolation and Biological Activities
AU - Naoki, Abe
AU - Yasukazu, Nakakita
AU - Takehiko, Nakamura
AU - Nobuyasu, Enoki
AU - Hideaki, Uchida
AU - Suguru, Takeo
AU - Masanobu, Munekata
PY - 1993/5
Y1 - 1993/5
N2 - In the course of our investigation aimed at the discovery of novel antitumor antibiotics from microorganisms, Streptomyces sp. G324 was found to produce the antitumor antibiotic, lavendamycin, and also, to yield the novel β-carboline compounds, oxopropalines. Weisolated five compoundsas oxopropalines A, B, D, E and G. Oxopropalines B, D and G showed cytocidal activities against humanor murine tumor cell lines in vitro.
AB - In the course of our investigation aimed at the discovery of novel antitumor antibiotics from microorganisms, Streptomyces sp. G324 was found to produce the antitumor antibiotic, lavendamycin, and also, to yield the novel β-carboline compounds, oxopropalines. Weisolated five compoundsas oxopropalines A, B, D, E and G. Oxopropalines B, D and G showed cytocidal activities against humanor murine tumor cell lines in vitro.
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UR - http://www.scopus.com/inward/citedby.url?scp=0027359619&partnerID=8YFLogxK
U2 - 10.7164/antibiotics.46.1672
DO - 10.7164/antibiotics.46.1672
M3 - Article
C2 - 8270488
AN - SCOPUS:0027359619
VL - 46
SP - 1672
EP - 1677
JO - Journal of Antibiotics
JF - Journal of Antibiotics
SN - 0021-8820
IS - 11
ER -