Novel aromatics bearing 4-O-methylglucose unit isolated from the oriental crude drug Bombyx Batryticatus

Haruhisa Kikuchi, Nahoko Takahashi, Yoshiteru Oshima

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

Oriental crude drug, Bombyx Batryticatus, is dried silkworm larva, Bombyx mori L., which are dead and stiffened due to a Beauveria bassiana infection. In traditional Japanese, Korean, and Chinese medicine, it is employed as analgesic and anticonvulsant. We investigated the constituents of Bombyx Batryticatus and isolated four novel aromatics bearing 4-O-methylglucose moiety, BB-1, 2, 3, and 4 (1-4). It is speculated that these compounds are produced by an interaction between plants, insects, and microorganisms.

Original languageEnglish
Pages (from-to)367-370
Number of pages4
JournalTetrahedron Letters
Volume45
Issue number2
DOIs
Publication statusPublished - 2004 Jan 5

Keywords

  • Beauveria bassiana
  • Biological interaction
  • Bombyx Batryticatus
  • Microbial biotransformation
  • Silkworm

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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