Novel antitumor antibiotics, saptomycins II. Isolation, physico-chemical properties and structure elucidation

Abe Naoki, Enoki Nobuyasu, Nakakita Yasukazu, Uchida Hideaki, Nakamura Takehiko, Munekata Masanobu

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

Acomplex of novel antitumor antibiotics related to the pluramycin-group was isolated from the fermentation of actinomycete, named Streptomyces sp. HP530. The producing strain mutated frequently. The products isolated from the parent strain were designated saptomycins A, B, C1, C2 and F, while those of the mutant were namedsaptomycins D, E, Gand H. These st.

Original languageEnglish
Pages (from-to)1536-1549
Number of pages14
Journalthe journal of antibiotics
Volume46
Issue number10
DOIs
Publication statusPublished - 1993 Feb
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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