Non-invasive blood glucose measurement using quantum cascade lasers

Yuji Matsuura, T. Koyama

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A non-invasive blood glucose measurement method using quantum cascade lasers (QCLs) oscillated in mid-infrared region is introduced. A mid-infrared spectroscopy system equipped with a combination of QCLs as light sources and hollow-optical fibers as beam delivery media is developed. As a wavelength of QCL, the wavenumber of 1152 cm-1 that exhibited strong correlation with blood glucose in the optical absorption of human lips is firstly chosen. Then 1186 cm-1 where glucose shows no absorption is also chosen as a reference to remove effects of the baseline variation. By using the QCL-based system, it is shown that the differential absorption between these wavelengths exhibits high correlation with blood glucose level.

Original languageEnglish
Title of host publicationQuantum Sensing and Nano Electronics and Photonics XVI
EditorsEric Tournie, Giti A. Khodaparast, Jay S. Lewis, Manijeh Razeghi
PublisherSPIE
ISBN (Electronic)9781510624948
DOIs
Publication statusPublished - 2019 Jan 1
EventQuantum Sensing and Nano Electronics and Photonics XVI 2019 - San Francisco, United States
Duration: 2019 Feb 32019 Feb 7

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume10926
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceQuantum Sensing and Nano Electronics and Photonics XVI 2019
CountryUnited States
CitySan Francisco
Period19/2/319/2/7

Keywords

  • ATR spectroscopy
  • Blood glucose
  • Hollow optical fiber
  • Quantum cascade laser

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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