No evidence for association between the interferon regulatory factor 1 (IRF1) gene and clinical tuberculosis

Sabine Vollstedt; Rika Yuliwulandari; Koji Okamoto; Luu Thi Lien; Naoto Keicho; Jecti Teguh Rochani; Riyani Wikaningrum; Katsushi Tokunaga

doi:10.1016/j.tube.2008.09.006

No evidence for association between the interferon regulatory factor 1 (IRF1) gene and clinical tuberculosis

Sabine Vollstedt, Rika Yuliwulandari, Koji Okamoto, Luu Thi Lien, Naoto Keicho, Jecti Teguh Rochani, Riyani Wikaningrum, Katsushi Tokunaga

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Interferon regulatory factor 1 is a transcription factor involved in initiating a vigorous Th1 response during Mycobacterium tuberculosis infection. Therefore, we considered it as a possible candidate gene for certain polymorphisms to confer susceptibility to develop clinical tuberculosis. However, all polymorphisms with minor allele frequencies higher than 5% and haplotype frequencies in two Southeast Asian populations (Indonesian and Vietnamese) turned out not to be associated with pulmonary tuberculosis.

Original language	English
Pages (from-to)	71-76
Number of pages	6
Journal	Tuberculosis
Volume	89
Issue number	1
DOIs	https://doi.org/10.1016/j.tube.2008.09.006
Publication status	Published - 2009 Jan 1
Externally published	Yes

Keywords

Interferon regulatory factor 1 (IRF1)
Tuberculosis

ASJC Scopus subject areas

Microbiology
Immunology
Microbiology (medical)
Infectious Diseases

Access to Document

10.1016/j.tube.2008.09.006

Fingerprint Dive into the research topics of 'No evidence for association between the interferon regulatory factor 1 (IRF1) gene and clinical tuberculosis'. Together they form a unique fingerprint.

Cite this

No evidence for association between the interferon regulatory factor 1 (IRF1) gene and clinical tuberculosis. / Vollstedt, Sabine; Yuliwulandari, Rika; Okamoto, Koji; Lien, Luu Thi; Keicho, Naoto; Rochani, Jecti Teguh; Wikaningrum, Riyani; Tokunaga, Katsushi.

In: Tuberculosis, Vol. 89, No. 1, 01.01.2009, p. 71-76.

Research output: Contribution to journal › Article › peer-review

@article{000a1fcc28764342b2aed3afc437a2a3,

title = "No evidence for association between the interferon regulatory factor 1 (IRF1) gene and clinical tuberculosis",

abstract = "Interferon regulatory factor 1 is a transcription factor involved in initiating a vigorous Th1 response during Mycobacterium tuberculosis infection. Therefore, we considered it as a possible candidate gene for certain polymorphisms to confer susceptibility to develop clinical tuberculosis. However, all polymorphisms with minor allele frequencies higher than 5% and haplotype frequencies in two Southeast Asian populations (Indonesian and Vietnamese) turned out not to be associated with pulmonary tuberculosis.",

keywords = "Interferon regulatory factor 1 (IRF1), Tuberculosis",

author = "Sabine Vollstedt and Rika Yuliwulandari and Koji Okamoto and Lien, {Luu Thi} and Naoto Keicho and Rochani, {Jecti Teguh} and Riyani Wikaningrum and Katsushi Tokunaga",

year = "2009",

month = jan,

day = "1",

doi = "10.1016/j.tube.2008.09.006",

language = "English",

volume = "89",

pages = "71--76",

journal = "Tuberculosis",

issn = "1472-9792",

publisher = "Churchill Livingstone",

number = "1",

}

TY - JOUR

T1 - No evidence for association between the interferon regulatory factor 1 (IRF1) gene and clinical tuberculosis

AU - Vollstedt, Sabine

AU - Yuliwulandari, Rika

AU - Okamoto, Koji

AU - Lien, Luu Thi

AU - Keicho, Naoto

AU - Rochani, Jecti Teguh

AU - Wikaningrum, Riyani

AU - Tokunaga, Katsushi

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Interferon regulatory factor 1 is a transcription factor involved in initiating a vigorous Th1 response during Mycobacterium tuberculosis infection. Therefore, we considered it as a possible candidate gene for certain polymorphisms to confer susceptibility to develop clinical tuberculosis. However, all polymorphisms with minor allele frequencies higher than 5% and haplotype frequencies in two Southeast Asian populations (Indonesian and Vietnamese) turned out not to be associated with pulmonary tuberculosis.

AB - Interferon regulatory factor 1 is a transcription factor involved in initiating a vigorous Th1 response during Mycobacterium tuberculosis infection. Therefore, we considered it as a possible candidate gene for certain polymorphisms to confer susceptibility to develop clinical tuberculosis. However, all polymorphisms with minor allele frequencies higher than 5% and haplotype frequencies in two Southeast Asian populations (Indonesian and Vietnamese) turned out not to be associated with pulmonary tuberculosis.

KW - Interferon regulatory factor 1 (IRF1)

KW - Tuberculosis

UR - http://www.scopus.com/inward/record.url?scp=58149109037&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58149109037&partnerID=8YFLogxK

U2 - 10.1016/j.tube.2008.09.006

DO - 10.1016/j.tube.2008.09.006

M3 - Article

C2 - 19028144

AN - SCOPUS:58149109037

VL - 89

SP - 71

EP - 76

JO - Tuberculosis

JF - Tuberculosis

SN - 1472-9792

IS - 1

ER -