Nisin Z produced by Lactococcus lactis subsp. lactis SBT 1212 and comparison of antibacterial activity with Nisin A

Yasushi Kawai, Hidetoshi Takada, Kei Konno, Boku Saitoh, Haruki Kitazawa, Tadao Saito, Hajime Nakajima, Honoo Hashiba, Takatoshi Itoh

Research output: Contribution to journalReview article

Abstract

Twenty-five lactococcal strains isolated from milk and fermented milk products were tested for bacteriocin production. Lactococcus lactis subsp. lactis SBT 1212 was the only strain producing nisin analogue which was classified to be nisin Z by chemical characterization and PCR amplification of structural genes. Antibacterial activities of nisin A (commercial product) and nisin Z (SBT 1212) against food-born pathogenic bacteria (gram-positive 10 and negative 6) were compared. The growth of Bacillus cereus JCM 2152, IFO 13494, IFO 13690, and Salmonella enteritidis IFO 3313 was more inhibited by nisin Z than by nisin A. To our knowledge, this is the first finding of the different activities of nisin A and Z.

Original languageEnglish
Pages (from-to)616-620
Number of pages5
JournalMilchwissenschaft
Volume54
Issue number11
Publication statusPublished - 1999 Dec 1

ASJC Scopus subject areas

  • Food Science

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