Nickel catalyzed imine aldol reactions between activated imines and pronucleophiles

Naomi Shida, Yasufumi Kubota, Hiroyuki Fukui, Naoki Asao, Isao Kadota, Yoshinori Yamamoto

    Research output: Contribution to journalArticle

    11 Citations (Scopus)

    Abstract

    Treatment of activated imines 1 with carbonyl compounds 2 in the presence of catalytic amounts of NiCl2(PPh3)2 or NiBr2(PPh3)2 at room temperature affords imine aldol products 3 in high to good yields.

    Original languageEnglish
    Pages (from-to)5023-5026
    Number of pages4
    JournalTetrahedron Letters
    Volume36
    Issue number28
    Publication statusPublished - 1995 Jul 26

    ASJC Scopus subject areas

    • Biochemistry
    • Drug Discovery
    • Organic Chemistry

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