New treatment for invasive fungal sinusitis: Three cases of chronic invasive fungal sinusitis treated with surgery and voriconazole

Kazuhiro Nakaya, Takeshi Oshima, Takayuki Kudo, Iori Aoyagi, Yukio Katori, Jun Ota, Hiroshi Hidaka, Kiyoshi Oda, Toshimitsu Kobayashi

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Invasive fungal sinusitis is a relatively rare disease and can be divided into acute fulminant, chronic, and granulomatous invasive fungal sinusitis. The conventional treatment is radical surgery combined with systemic amphotericin B administration, but the poor prognosis and unestablished treatment options require a better therapeutic strategy. We report three cases of chronic invasive fungal sinusitis successfully treated with a combination of surgery and voriconazole, a new antifungal agent, with good responses in all patients. Voriconazole administration could form the basis for a new standard treatment for invasive fungal sinusitis.

Original languageEnglish
Pages (from-to)244-249
Number of pages6
JournalAuris Nasus Larynx
Volume37
Issue number2
DOIs
Publication statusPublished - 2010 Apr

Keywords

  • Amphotericin B
  • Chronic invasive fungal sinusitis
  • Voriconazole

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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