The diazoketones (3a and b) and the iminomalonates (7a and b) have been converted into the tetracyclic vinylogous amides (6a and b) by an acid-catalysed single-step reaction; Birch reduction of the amides (6a and b) afforded the corresponding tetracyclic ketones (2a and b), synthons for the synthesis of functionalized aspidosperma alkaloids.
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - 1978|
ASJC Scopus subject areas
- Molecular Medicine