New synthetic route to the highly strained cores of C-1027 and neocarzinostatin chromophores

I. Sato, K. Toyama, T. Kikuchi, M. Hirama

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

Efficient construction of the bicyclo[7.3.0]dodecenediyne cores of chromophore of C-1027 (1) and neocarzinostatin (2) was obtained via the C-C bond formation at C5-C6 using the LiN(SiMe3)2/ CeCl3-mediated acetylide-aldehyde condensation reaction.

Original languageEnglish
Pages (from-to)1308-1310
Number of pages3
JournalSynlett
Issue number12
DOIs
Publication statusPublished - 1998 Dec

ASJC Scopus subject areas

  • Organic Chemistry

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