TY - JOUR
T1 - NEW SUGAR BASED γ-AMINO SILYL ETHER ORGANOCATALYSTS FOR ASYMMETRIC MICHAEL ADDITION OF β-KETO ESTERS WITH NITROOLEFINS
AU - Ganesan, Divakar
AU - Parasuraman, Perumalsamy
AU - Begum, Zubeda
AU - Thiyagarajan, Rajkumar
AU - Seki, Chigusa
AU - Okuyama, Yuko
AU - Kwon, Eunsang
AU - Uwai, Koji
AU - Tokiwa, Michio
AU - Tokiwa, Suguru
AU - Takeshita, Mitsuhiro
AU - Nakano, Hiroto
N1 - Publisher Copyright:
© 2022 The Japan Institute of Heterocyclic Chemistry.
PY - 2022
Y1 - 2022
N2 - New sugar based γ-amino silyl ether organocatalysts were synthesized and their catalytic ability was examined in asymmetric Michael addition of β-keto esters with nitroolefins affording chiral Michael adducts with quaternary carbon stereocenter in good to excellent chemical yields, diastereoselectivities and moderate enantioselectivities (up to 97%, up to dr. 85:15, up to 56% ee).
AB - New sugar based γ-amino silyl ether organocatalysts were synthesized and their catalytic ability was examined in asymmetric Michael addition of β-keto esters with nitroolefins affording chiral Michael adducts with quaternary carbon stereocenter in good to excellent chemical yields, diastereoselectivities and moderate enantioselectivities (up to 97%, up to dr. 85:15, up to 56% ee).
UR - http://www.scopus.com/inward/record.url?scp=85133877000&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85133877000&partnerID=8YFLogxK
U2 - 10.3987/COM-21-S(R)2
DO - 10.3987/COM-21-S(R)2
M3 - Article
AN - SCOPUS:85133877000
SN - 0385-5414
VL - 105
SP - 369
EP - 382
JO - Heterocycles
JF - Heterocycles
IS - 1
ER -