New nanocomposite biomaterials controlling surface and bulk properties using supercritical carbon dioxide

Tora Hoshi, Takashi Sawagushi, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The molecular composite composed of polyethylene (PE) and polyvinyl acetate) (PVAc) prepared using supercritical carbon dioxide (scCO2) and its surface modification for biocompatible surface demonstrated the creation of novel polymer biomaterials. In this study, this modification process was applied to the PE narrow tube (inside diameter: 300μm, outside diameter: 600μm, length: 5m) It was confirmed that PVAc was uniformly generated in PE tube by infrared imaging measurement of cross-section. After the acetyl group on the surface was hydrolyzed, phospholipid polymer was immobilized to the hydroxyl group on the surface of the tube. The phospholipid polymer immobilized surface showed a drastic reduction in protein adsorption. The surface of the minute and slender tube can be effectively modified using the feature of carbon dioxide whose surface tension is near zero. The modification technology by scCO2 is a promising for creation of variously-shaped new biomaterials.

Original languageEnglish
Title of host publicationMechanical Behavior of Biological Materials and Biomaterials
PublisherMaterials Research Society
Pages58-64
Number of pages7
ISBN (Print)9781605608525
DOIs
Publication statusPublished - 2008 Jan 1
Externally publishedYes
Event2008 MRS Spring Meeting - San Francisco, CA, United States
Duration: 2008 Mar 242008 Mar 28

Publication series

NameMaterials Research Society Symposium Proceedings
Volume1097
ISSN (Print)0272-9172

Other

Other2008 MRS Spring Meeting
CountryUnited States
CitySan Francisco, CA
Period08/3/2408/3/28

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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  • Cite this

    Hoshi, T., Sawagushi, T., Matsuno, R., Konno, T., Takai, M., & Ishihara, K. (2008). New nanocomposite biomaterials controlling surface and bulk properties using supercritical carbon dioxide. In Mechanical Behavior of Biological Materials and Biomaterials (pp. 58-64). (Materials Research Society Symposium Proceedings; Vol. 1097). Materials Research Society. https://doi.org/10.1557/proc-1097-gg04-15