New cytotoxic phenolic derivatives from matured fruits of magnolia denudata

Toshiro Noshita, Hiromasa Kiyota, Yumi Kidachi, Kazuo Ryoyama, Shinji Funayama, Ken Hanada, Tetsuya Murayama

    Research output: Contribution to journalArticlepeer-review

    17 Citations (Scopus)


    Magnolia species are widely cultivated in Japan as garden plants, and have been found to contain various compounds, including alkaloids, terpenoids, lignans, and neolignans. The constituents of the mature fruits of M. denudata were investigated, and two new phenolic derivatives, named denudalide and denudaquinol, were isolated and characterized, together with a known neolignan compound (denudatin A). Denudalide and denudaquinol showed cytotoxicity against the SFME and r/mHM-SFME-1 cell lines.

    Original languageEnglish
    Pages (from-to)726-728
    Number of pages3
    JournalBioscience, Biotechnology and Biochemistry
    Issue number3
    Publication statusPublished - 2009


    • Benzofuranone
    • Cytotoxic metabolite
    • Denudalide
    • Denudaquinol
    • Magnolia denudata

    ASJC Scopus subject areas

    • Biotechnology
    • Analytical Chemistry
    • Biochemistry
    • Applied Microbiology and Biotechnology
    • Molecular Biology
    • Organic Chemistry


    Dive into the research topics of 'New cytotoxic phenolic derivatives from matured fruits of magnolia denudata'. Together they form a unique fingerprint.

    Cite this