Abstract
The synthesis of the progesterone BCD-ring system utilizing a tandem transannular radical cyclization and its diastereoselectivity based on MM2 transition state model calculations (flexible model) are described.
Original language | English |
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Pages (from-to) | 2363-2366 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 40 |
Issue number | 12 |
DOIs | |
Publication status | Published - 1999 Mar 19 |
Externally published | Yes |
Keywords
- Molecular modelling/mechanics
- Radicals and radical reactions
- Steroids and sterols
- Transannular reactions
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry