New 6/8/6-taxanes isolated from the heartwood of taxus cuspidata

Kai Zhang, Yong Li, Zhi Yi Ni, Man Li Zhang, Yu Fang Wang, Qing Wen Shi, Chang Hong Huo, Françoise Sauriol, Hiromasa Kiyota, Yu Cheng Gu, Mei Dong

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)

    Abstract

    Two new natural taxanes were isolated from the heartwood of Taxus cuspidata. The structures were established as rel-(2α,5α,7β, 9α,10β,12α)-7,9-bis(acetyloxy)-2-(benzoyloxy)-11,12-epoxy-1, 5-dihydroxy-10-[(hydroxyacetyl)oxy]tax-4(20)-en-13-one (1), and (2α,5α,10β,14β)-taxa-4(20),11-diene-2,5,10,14-tetrol 2-acetate (2) on the basis of spectroscopic analysis.

    Original languageEnglish
    Pages (from-to)1566-1572
    Number of pages7
    JournalHelvetica Chimica Acta
    Volume95
    Issue number9
    DOIs
    Publication statusPublished - 2012 Sep

    Keywords

    • Taxanes
    • Taxus cuspidata

    ASJC Scopus subject areas

    • Catalysis
    • Biochemistry
    • Drug Discovery
    • Physical and Theoretical Chemistry
    • Organic Chemistry
    • Inorganic Chemistry

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