Neuropsychology of epilepsy

H. Matsuoka

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Purpose: The neuropsychological approach to epilepsy is indispensable for assessment of cognitive function in an interictal period including pre- and postsurgical evaluation, and for disclosing the semiology of nonconvulsive status epilepticus. Another use of the neuropsychological approach is to identify a seizure-precipitating factor by loading systematic cognitive tasking, termed "neuropsychological EEG activation" (NPA), during standard EEG recordings. Methods.: In this study, NPA tasks consisted of reading, speaking, writing, written arithmetic calculation, mental arithmetic calculation, and spatial construction. Results: The NPA tasks provoked epileptic discharges in 7.9% of the 480 epileptic patients and were often accompanied by myoclonic seizures. Among the cognitive tasks, mental activities mainly associated with use of the hands [i.e., writing (68.4%), written calculation (55.3%), and spatial construction (63.2%)] provoked the most discharges. Seizure-precipitating mental activities were found to be almost exclusively related to idiopathic generalized epilepsies (IGEs). Conclusions: These results suggest that NPA is a useful tool for examining the relationship between cognitive function and epileptic seizures, and that the IGE patients with myoclonic seizures are vulnerable to higher mental activity.

Original languageEnglish
Pages (from-to)42-46
Number of pages5
JournalEpilepsia
Volume42
Issue numberSUPPL. 8
DOIs
Publication statusPublished - 2001

Keywords

  • EEG activation
  • Idiopathic generalized epilepsy
  • Juvenile myoclonic epilepsy
  • Myoclonic seizure
  • Neuropsychology

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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