Abstract
This conference proceeding describes a preliminary report of a method for construction of in vitro neural circuits with control over cell morphology and connectivity by assembling morphologically controlled single neural cells. In our previous work [1], we reported mobile microplates that enable morphological control and handling of single neural cells. Here, we assembled the microplates loading morphologically controlled single neural cells into circuit-like structures. We show that assembly of the microplates could guide cell-cell contacts between individual cells. We believe the method would be useful in in vitro neural network construction for studies of synaptogenesis and neural information processing.
| Original language | English |
|---|---|
| Title of host publication | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 861-862 |
| Number of pages | 2 |
| ISBN (Electronic) | 9780979806476 |
| Publication status | Published - 2014 Jan 1 |
| Externally published | Yes |
| Event | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States Duration: 2014 Oct 26 → 2014 Oct 30 |
Other
| Other | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
|---|---|
| Country/Territory | United States |
| City | San Antonio |
| Period | 14/10/26 → 14/10/30 |
Keywords
- Bio-MEMS
- Cell handling
- Micromanipulation
- Morphology
- Neural cell
- Neural circuit
ASJC Scopus subject areas
- Control and Systems Engineering