Neural circuit assembly using morphologically controlled single neural cells

Shotaro Yoshida, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This conference proceeding describes a preliminary report of a method for construction of in vitro neural circuits with control over cell morphology and connectivity by assembling morphologically controlled single neural cells. In our previous work [1], we reported mobile microplates that enable morphological control and handling of single neural cells. Here, we assembled the microplates loading morphologically controlled single neural cells into circuit-like structures. We show that assembly of the microplates could guide cell-cell contacts between individual cells. We believe the method would be useful in in vitro neural network construction for studies of synaptogenesis and neural information processing.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages861-862
Number of pages2
ISBN (Electronic)9780979806476
Publication statusPublished - 2014 Jan 1
Externally publishedYes
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 2014 Oct 262014 Oct 30

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period14/10/2614/10/30

Keywords

  • Bio-MEMS
  • Cell handling
  • Micromanipulation
  • Morphology
  • Neural cell
  • Neural circuit

ASJC Scopus subject areas

  • Control and Systems Engineering

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