Neural activity-dependent regulation of gene expression in developing and mature neurons

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)

Abstract

Neurons can change their gene expression patterns according to the inputs they have received. This activity-dependent gene regulation mechanism plays an important role in the formation of neural circuits during development. Further, by regulating the synaptic plasticity, this mechanism may function as an essential one for each organism to adapt flexibly to its environment. This review summarizes our current knowledge about the activity-dependent gene regulation mechanism in neurons, focusing on the transcription factors and signaling pathways involved in this mechanism.

Original languageEnglish
Pages (from-to)261-271
Number of pages11
JournalDevelopment Growth and Differentiation
Volume50
Issue number4
DOIs
Publication statusPublished - 2008 May 1
Externally publishedYes

Keywords

  • Memory
  • Neural development
  • Synaptic activity
  • Synaptic plasticity
  • Transcription factor

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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