Neural activity-dependent regulation of gene expression in developing and mature neurons

Kentaro Abe

doi:10.1111/j.1440-169X.2008.00999.x

Neural activity-dependent regulation of gene expression in developing and mature neurons

Kentaro Abe

Research output: Contribution to journal › Review article › peer-review

6 Citations (Scopus)

Abstract

Neurons can change their gene expression patterns according to the inputs they have received. This activity-dependent gene regulation mechanism plays an important role in the formation of neural circuits during development. Further, by regulating the synaptic plasticity, this mechanism may function as an essential one for each organism to adapt flexibly to its environment. This review summarizes our current knowledge about the activity-dependent gene regulation mechanism in neurons, focusing on the transcription factors and signaling pathways involved in this mechanism.

Original language	English
Pages (from-to)	261-271
Number of pages	11
Journal	Development Growth and Differentiation
Volume	50
Issue number	4
DOIs	https://doi.org/10.1111/j.1440-169X.2008.00999.x
Publication status	Published - 2008 May 1
Externally published	Yes

Keywords

Memory
Neural development
Synaptic activity
Synaptic plasticity
Transcription factor

ASJC Scopus subject areas

Developmental Biology
Cell Biology

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10.1111/j.1440-169X.2008.00999.x

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KW - Neural development

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KW - Synaptic plasticity

KW - Transcription factor

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