Nested polymerase chain reaction for detection of Mycobacterium tuberculosis in clinical samples

Y. Miyazaki, H. Koga, S. Kohno, M. Kaku

Research output: Contribution to journalComment/debatepeer-review

87 Citations (Scopus)

Abstract

The nested polymerase chain reaction technique was compared with the conventional smear and culture methods for detection of Mycobacterium tuberculosis. The nested polymerase chain reaction used in this study showed excellent specificity, sensitivity, and agreement with the conventional methods for 417 clinical samples, indicating a contribution to the rapid diagnosis of mycobacterial infectious diseases.

Original languageEnglish
Pages (from-to)2228-2232
Number of pages5
JournalJournal of Clinical Microbiology
Volume31
Issue number8
DOIs
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Microbiology (medical)

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