Near-infrared spectroscopy of orbitofrontal cortex during odorant stimulation

Norio Kokan, Nobuyuki Sakai, Kiyoshi Doi, Hisami Fujio, Shingo Hasegawa, Hitoshi Tanimoto, Ken Ichi Nibu

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Background: For olfaction, several studies have reported near-infrared spectroscopy (NIRS) signal changes in the orbitofrontal cortex (OFC) during odor stimulation. However, the roles of human OFC in olfactory cognition are less well understood. This study was designed to better understand the roles of OFC for olfaction. Methods: Hemodynamic responses for phenyl ethyl alcohol or citral in the OFCs were measured with NIRS. After the experiment, participants were asked to describe the characteristics of the odor and to rate odor intensity and hedonic valence. Results: Statistical analysis of all participants' data showed significant changes in the concentration of total hemoglobin in the left OFC during the trial (p = 0.04). The total hemoglobin signal increased significantly in the right OFC (p = 0.0008) of the participants who successfully identified the odorant stimulus. Conclusion: Our findings showed that NIRS combined with a questionnaire is a useful method for studying the functional neuroanatomy of OFC in terms of olfaction.

Original languageEnglish
Pages (from-to)163-165
Number of pages3
JournalAmerican Journal of Rhinology and Allergy
Volume25
Issue number3
DOIs
Publication statusPublished - 2011 May
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Otorhinolaryngology

Fingerprint Dive into the research topics of 'Near-infrared spectroscopy of orbitofrontal cortex during odorant stimulation'. Together they form a unique fingerprint.

Cite this