The hemolymph of the marine snail Tugali gigas contains a potent hemolysin. Hemolysin was a protein in nature, and was heat-labile. Hemolytic activity was dependent on the presence of calcium ions. It was sensitive to the treatment with 2-mercaptoethanoI or trypsin. Freezing the hemolymph also destroyed the hemolytic activity. The sugars such as D-mannosamine, AT-acetyl-D-mannosamine, and also mucin Type II depressed the hemolytic activity of the hemolymph. Zymosan or sphingomyelin did not absorb the hemolysin in the T. gigas hemolymph. No cyto-toxicity against murine tumor cells nor the growth inhibition against a marine bacterium were observed.
ASJC Scopus subject areas
- Aquatic Science