Naturally Occurring Hemolysin in the Marine Snail Tugali gigas

Hisao Kamiya, Koji Muramoto, Rina Goto

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    2 Citations (Scopus)


    The hemolymph of the marine snail Tugali gigas contains a potent hemolysin. Hemolysin was a protein in nature, and was heat-labile. Hemolytic activity was dependent on the presence of calcium ions. It was sensitive to the treatment with 2-mercaptoethanoI or trypsin. Freezing the hemolymph also destroyed the hemolytic activity. The sugars such as D-mannosamine, AT-acetyl-D-mannosamine, and also mucin Type II depressed the hemolytic activity of the hemolymph. Zymosan or sphingomyelin did not absorb the hemolysin in the T. gigas hemolymph. No cyto-toxicity against murine tumor cells nor the growth inhibition against a marine bacterium were observed.

    Original languageEnglish
    Pages (from-to)2109-2113
    Number of pages5
    JournalNippon Suisan Gakkaishi (Japanese Edition)
    Issue number11
    Publication statusPublished - 1991 Jan 1

    ASJC Scopus subject areas

    • Aquatic Science


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