TY - JOUR
T1 - Naturally Occurring Hemolysin in the Marine Snail Tugali gigas
AU - Kamiya, Hisao
AU - Muramoto, Koji
AU - Goto, Rina
PY - 1991/1/1
Y1 - 1991/1/1
N2 - The hemolymph of the marine snail Tugali gigas contains a potent hemolysin. Hemolysin was a protein in nature, and was heat-labile. Hemolytic activity was dependent on the presence of calcium ions. It was sensitive to the treatment with 2-mercaptoethanoI or trypsin. Freezing the hemolymph also destroyed the hemolytic activity. The sugars such as D-mannosamine, AT-acetyl-D-mannosamine, and also mucin Type II depressed the hemolytic activity of the hemolymph. Zymosan or sphingomyelin did not absorb the hemolysin in the T. gigas hemolymph. No cyto-toxicity against murine tumor cells nor the growth inhibition against a marine bacterium were observed.
AB - The hemolymph of the marine snail Tugali gigas contains a potent hemolysin. Hemolysin was a protein in nature, and was heat-labile. Hemolytic activity was dependent on the presence of calcium ions. It was sensitive to the treatment with 2-mercaptoethanoI or trypsin. Freezing the hemolymph also destroyed the hemolytic activity. The sugars such as D-mannosamine, AT-acetyl-D-mannosamine, and also mucin Type II depressed the hemolytic activity of the hemolymph. Zymosan or sphingomyelin did not absorb the hemolysin in the T. gigas hemolymph. No cyto-toxicity against murine tumor cells nor the growth inhibition against a marine bacterium were observed.
UR - http://www.scopus.com/inward/record.url?scp=85010170755&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85010170755&partnerID=8YFLogxK
U2 - 10.2331/suisan.57.2109
DO - 10.2331/suisan.57.2109
M3 - Article
AN - SCOPUS:85010170755
VL - 57
SP - 2109
EP - 2113
JO - Nippon Suisan Gakkaishi
JF - Nippon Suisan Gakkaishi
SN - 0021-5392
IS - 11
ER -
