National survey of pediatric hospitalizations due to Kawasaki disease and coronary artery aneurysms in the USA

Yusuke Okubo, Kotaro Nochioka, Hiroshi Sakakibara, Marcia Testa, Robert P. Sundel

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Several studies revealed the epidemiology of Kawasaki disease-related hospitalizations among children in the USA and other countries. However, disparities of developing coronary artery aneurysms by race/ethnicity, patient socioeconomic status, and geographic locations remain unknown in the USA. Hospital discharge record data of patients with Kawasaki disease aged 19 years or younger were obtained from the 2003, 2006, 2009, and 2012 Kid’s Inpatient Database. The data were weighted to estimate the annual hospitalization rates with respect to age, gender, and race/ethnicity in the USA. Multivariable logistic regression was conducted to ascertain the factors associated with the development of coronary artery aneurysms. Total annual hospitalization rates of Kawasaki disease showed a decreasing trend, ranging from 6.54 per 100,000 children in 2003 to 6.11 per 100,000 children in 2012 (p < 0.001). The proportions of coronary artery aneurysms among patients with Kawasaki disease ranged from 2.25 to 3.20%. Factor associated with the development of coronary artery aneurysms was hospitals in West (OR 2.15, 95% CI 1.42–3.26). Race/ethnicity, health insurance status, and household income were not associated with the development of coronary artery aneurysms. Total hospitalization rates of Kawasaki disease showed a decreasing trend. Children admitted to hospitals in West region were more likely to develop coronary artery aneurysms.

Original languageEnglish
Pages (from-to)413-419
Number of pages7
JournalClinical Rheumatology
Volume36
Issue number2
DOIs
Publication statusPublished - 2017 Feb 1
Externally publishedYes

Keywords

  • Coronary artery aneurysm
  • Kawasaki disease
  • Kids Inpatient Database

ASJC Scopus subject areas

  • Rheumatology

Fingerprint Dive into the research topics of 'National survey of pediatric hospitalizations due to Kawasaki disease and coronary artery aneurysms in the USA'. Together they form a unique fingerprint.

Cite this