Nanoscale cell surface topography imaging using scanning ion conductance microscopy

Yasufumi Takahashi, Komachi Ito, Xiongwei Wang, Yoshiharu Matsumae, Hirokazu Komaki, Akichika Kumatani, Kosuke Ino, Hitoshi Shiku, Tomokazu Matsue

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


Nanoscale cell surface topography was visualized using a scanning ion conductance microscope (SICM), where a nanopipette was used as the scanning probe to detect ionic current as feedback signal. SICM was an effective tool for noncontact topographical imaging of live cells, because measurements were performed under physiological conditions. This breakthrough technique opens up a wealth of possible new experiments in membrane and cell biology.

Original languageEnglish
Pages (from-to)331-334
Number of pages4
Issue number5
Publication statusPublished - 2014 May


  • Live Cell Imaging
  • Nanoscale Imaging
  • SICM

ASJC Scopus subject areas

  • Electrochemistry


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