Nanoscale cell surface topography imaging using scanning ion conductance microscopy

Yasufumi Takahashi; Komachi Ito; Xiongwei Wang; Yoshiharu Matsumae; Hirokazu Komaki; Akichika Kumatani; Kosuke Ino; Hitoshi Shiku; Tomokazu Matsue

doi:10.5796/electrochemistry.82.331

Nanoscale cell surface topography imaging using scanning ion conductance microscopy

Yasufumi Takahashi, Komachi Ito, Xiongwei Wang, Yoshiharu Matsumae, Hirokazu Komaki, Akichika Kumatani, Kosuke Ino, Hitoshi Shiku, Tomokazu Matsue

Research output: Contribution to journal › Article

14 Citations (Scopus)

Abstract

Nanoscale cell surface topography was visualized using a scanning ion conductance microscope (SICM), where a nanopipette was used as the scanning probe to detect ionic current as feedback signal. SICM was an effective tool for noncontact topographical imaging of live cells, because measurements were performed under physiological conditions. This breakthrough technique opens up a wealth of possible new experiments in membrane and cell biology.

Original language	English
Pages (from-to)	331-334
Number of pages	4
Journal	Electrochemistry
Volume	82
Issue number	5
DOIs	https://doi.org/10.5796/electrochemistry.82.331
Publication status	Published - 2014 May

Keywords

Live Cell Imaging
Nanoscale Imaging
SICM

ASJC Scopus subject areas

Electrochemistry

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Takahashi, Y., Ito, K., Wang, X., Matsumae, Y., Komaki, H., Kumatani, A., Ino, K., Shiku, H., & Matsue, T. (2014). Nanoscale cell surface topography imaging using scanning ion conductance microscopy. Electrochemistry, 82(5), 331-334. https://doi.org/10.5796/electrochemistry.82.331

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AU - Takahashi, Yasufumi

AU - Ito, Komachi

AU - Wang, Xiongwei

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AU - Kumatani, Akichika

AU - Ino, Kosuke

AU - Shiku, Hitoshi

AU - Matsue, Tomokazu

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