Nanometer-scale patterned surfaces for control of cell adhesion

Makiko Goto, Takehiko Tsukahara, Kae Sato, Tomohiro Konno, Kazuhiko Ishihara, Kiichi Sato, Takehiko Kitamori

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)


A novel cell-adhesion surface, controlled by nanometer-scale topography and chemical patterning, was developed using semiconductor fabrication methods and the formation of self-assembled monolayers. The patterned surface had a sharp contrast between the adsorption and non-adsorption of proteins and cells, and the contrast could be maintained for more than 10 days. The patterning method could easily realize a single cell array and control of the cell morphology. The nanometer-scale patterned surface could control cell adhesion and proliferation. Using the patterned surface will contribute to studies about cell-surface interactions. 2007

Original languageEnglish
Pages (from-to)245-247
Number of pages3
Journalanalytical sciences
Issue number3
Publication statusPublished - 2007 Mar
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry


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