Nanogels of hydrophobized polysaccharides: Structure of polysaccharides

Eri Akiyama, Nobuyuki Morimoto, Kazunari Akiyoshi

Research output: Contribution to conferencePaperpeer-review


We investigated solution properties of cholesteryl-bearing mannan (CHM), which is higher branch structure. CHM formed self-aggregates in dilute aqueous solution. Using SEC-MALS and fluorescence-quenching technique, the self-aggregate consists of ∼7.5 CHM molecules and the aggregation number of cholesteryl moieties in one hydrophobic domain was ∼10. Cholesteryl-bearing pullulan (CHP) formed macrogel above 3.5wt% due to the connection of CHP nanogels. However, no gelation was observed even in the concentration of 10wt% of CHM. CHM nanogels showed higher colloidal stability than CHP nanogels. The branched structure of polysaccharides of nanogels affects solution property.

Original languageEnglish
Number of pages1
Publication statusPublished - 2005 Dec 1
Externally publishedYes
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: 2005 May 252005 May 27


Other54th SPSJ Annual Meeting 2005


  • Cholesterol
  • Hydrophobized polysaccharide
  • Mannan
  • Nanogel
  • Pullulan
  • Self-assembly

ASJC Scopus subject areas

  • Engineering(all)


Dive into the research topics of 'Nanogels of hydrophobized polysaccharides: Structure of polysaccharides'. Together they form a unique fingerprint.

Cite this