Nano-dynamics of living cell surface by AFM

Takaharu Okajima, Masaru Tanaka, Shusaku Tsukiyama, Sadaaki Yamamoto, Masatsugu Shimomura, Hiroshi Tokumoto

    Research output: Contribution to conferencePaperpeer-review


    Dynamics of living cell surface, hepatocyte was measured with an atomic force microscope (AFM). A thermal fluctuation spectroscopy, in which the thermal noise of cantilever is monitored to estimate the mechanical properties of sample surfaces, was for the first time applied to living cells. The power spectrum of cantilevers was analyzed using a harmonic oscillator with memory function of the friction coefficient. The results showed that the friction coefficient decreased with increasing the frequency in the range of 1-20 kHz, indicating the dispersion of the cell surface friction coefficient in the microsecond time domain.

    Original languageEnglish
    Number of pages1
    Publication statusPublished - 2006 Oct 19
    Event55th SPSJ Annual Meeting - Nagoya, Japan
    Duration: 2006 May 242006 May 26


    Other55th SPSJ Annual Meeting


    • Atomic force microscope (AFM)
    • Living Cells
    • Nano-Dynamics
    • Surface

    ASJC Scopus subject areas

    • Engineering(all)


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