TY - JOUR
T1 - N-heterocyclic carbenes catalyzed umpolung reactions via homoenolates
AU - Adachi, Masaatsu
PY - 2007/10
Y1 - 2007/10
N2 - Polarity inversion (umpolung or charge affinity inversion) of functional groups is widely recognized as a powerful and efficient synthetic method because it makes possible not only to offer strategic flexibilities but also to form carbon-carbon bonds in the design of complex molecules. Recently, the new approaches of carbonyl synthons employing N-heterocyclic carbene catalyzed homoenolate reactions have been utilized in a variety of applications. In this review, the chemistry highlight in development of the catalytic generation of homoenolates and their application to the novel carbon-carbon bond-forming process is described.
AB - Polarity inversion (umpolung or charge affinity inversion) of functional groups is widely recognized as a powerful and efficient synthetic method because it makes possible not only to offer strategic flexibilities but also to form carbon-carbon bonds in the design of complex molecules. Recently, the new approaches of carbonyl synthons employing N-heterocyclic carbene catalyzed homoenolate reactions have been utilized in a variety of applications. In this review, the chemistry highlight in development of the catalytic generation of homoenolates and their application to the novel carbon-carbon bond-forming process is described.
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U2 - 10.5059/yukigoseikyokaishi.65.1009
DO - 10.5059/yukigoseikyokaishi.65.1009
M3 - Article
AN - SCOPUS:38049120285
VL - 65
SP - 1009
EP - 1010
JO - Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
JF - Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
SN - 0037-9980
IS - 10
ER -