Myocardial imaging using 11CCoQ10 with positron emission tomography

Yuka Miura, Yutaka Kagaya, Eiji Nozaki, Nobumasa Ishide, Yukio Maruyama, Tamotsu Takishima, Toshihiro Takahashi, Kiichi Ishiwata, Shouichi Watanuki, Tatsuo Ido

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The potential of 11C-labeled coenzyme Q10(CoQ10) as a myocardial imaging tracer was explored with positron emission tomography (PET). Serial myocardial imaging studies were performed using 11C-CoQ10, 45Ti-diethylenetriaminepentaacetic acid (45Ti-DTPA), and 2-deoxy-2-[18F]fluoro-d-mannose (18FDM) in the same dog. Cross sectional images of the heart with 11C-CoQ10 showed relatively high radioactivity in the blood pool, when compared with images taken with 18FDM. However, when the blood spillover of radioactivity is adequately corrected with 45Ti-DTPA data, it was found that 11C-CoQ10 accumulated in the myocardium with time.

Original languageEnglish
Pages (from-to)1-3,5-6
JournalInternational Journal of Radiation Applications and Instrumentation.
Volume14
Issue number1
DOIs
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Medicine(all)

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