Mumiamicin: Structure and bioactivity of a new furan fatty acid from Mumia sp. YSP-2-79

Tōru Kimura, Ayano Tajima, Yuki Inahashi, Masato Iwatsuki, Hiroaki Kasai, Takayuki Mokudai, Yoshimi Niwano, Kazuro Shiomi, Yōko Takahashi, Satoshi Ōmura, Takuji Nakashima

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A new antibiotic, designated mumiamicin, was isolated from the cultured broth of the rare actinomycete strain, Mumia sp. YSP-2-79, by Diaion HP-20, silica gel and ODS column chromatography, followed by HPLC purification. The chemical structure of mumiamicin was elucidated as a new furan fatty acid by nuclear magnetic resonance and mass spectrometry. Mumiamicin showed antimicrobial activity and antioxidative activity.

Original languageEnglish
Pages (from-to)62-67
Number of pages6
JournalJournal of General and Applied Microbiology
Volume64
Issue number2
DOIs
Publication statusPublished - 2018 Jan 1

Keywords

  • Antioxidative activity
  • Furan fatty acid
  • Marine actinomycete
  • Mumiamicin
  • Physicochemical screening

ASJC Scopus subject areas

  • Microbiology
  • Applied Microbiology and Biotechnology

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    Kimura, T., Tajima, A., Inahashi, Y., Iwatsuki, M., Kasai, H., Mokudai, T., Niwano, Y., Shiomi, K., Takahashi, Y., Ōmura, S., & Nakashima, T. (2018). Mumiamicin: Structure and bioactivity of a new furan fatty acid from Mumia sp. YSP-2-79. Journal of General and Applied Microbiology, 64(2), 62-67. https://doi.org/10.2323/jgam.2017.06.004