Multivariate analysis reveals oral health-related quality of life of complete denture wearers with denture adhesives: A multicenter randomized controlled trial

Yoshihiko Ito, Guang Hong, Akito Tsuboi, Yasuhiko Kawai, Hisatomo Kondo, Taro Nomura, Suguru Kimoto, Atsuko Gunji, Asako Suzuki, Gaku Ohwada, Shunsuke Minakuchi, Yusuke Sato, Tetsuya Suzuki, Katsuhiko Kimoto, Noriyuki Hoshi, Makiko Saita, Yoshikazu Yoneyama, Yohei Sato, Masakazu Morokuma, Joji OkazakiTakeshi Maeda, Kenichiro Nakai, Tetsuo Ichikawa, Kan Nagao, Keiko Fujimoto, Hiroshi Murata, Tadafumi Kurogi, Kazuma Takase, Masahiro Nishimura, Yasuhiro Nishi, Mamoru Murakami, Toshio Hosoi, Taizo Hamada

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Purpose: To investigate the difference in improvement of oral health-related quality of life (OHR-QoL) depending on the oral and denture conditions of a complete denture wearer when using a cream or powder type denture adhesive in a 10-center parallel randomized clinical trial. Methods: Two hundred edentulous subjects who wore complete dentures were allocated to each of the three groups according to denture adhesive type: cream, powder, and control (saline solution). The materials were applied to the mucosal surface of the dentures for 4 days, and baseline data and data after the intervention were collected. OHR-QoL was assessed using the Japanese version of the modified Oral Health Impact Profile for Edentulous Patients (OHIP-EDENT-J) scale for outcome. Multivariate analysis was used to investigate improvements in OHR-QoL according to participant characteristics among complete denture wearers using these materials. Results: OHIP-EDENT-J scores were significantly decreased in all groups after the intervention (p < 0.05); however, there were no statistically significant differences among the groups. Multiple logistic regression analysis revealed a significant association between the vertical height of the maxillary and mandibular alveolar ridge and OHIP-EDENT-J scores in the cream-type denture adhesive group. In contrast, there were no significant association between participant characteristics and OHIP-EDENT-J scores in the powder-type adhesive and control groups. Conclusions: The use of denture adhesives could improve OHR-QoL for complete denture wearers. The cream-type denture adhesives may be expected to improve OHR-QoL in patients with poor residual ridge conditions compared with patients with good residual ridge conditions.

Original languageEnglish
Pages (from-to)353-359
Number of pages7
JournalJournal of Prosthodontic Research
Volume65
Issue number3
DOIs
Publication statusPublished - 2021

Keywords

  • Complete denture
  • Denture adhesive
  • Multivariate analysis
  • OHR-QoL

ASJC Scopus subject areas

  • Oral Surgery
  • Dentistry (miscellaneous)

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