In the present paper, multiscale simulation model for CFRP plate structure is proposed. The method is based on the homogenization theory and Reissner-Mindlin plate theory. In the model, CFRP plate structure is modeled in two scales: microscopic and macroscopic. In the microscopic scale full 3-dimensional displacement field is considered, whereas in the macroscopic scale displacement field is assumed to be described by Reissner-Mindlin plate theory. Material properties, stress and strain are exchanged between these two scales each other based on the homogenization method. The model was validated by two methods. First, the stiffness matrix calculated by the microscopic model was compared to that was predicted by classical lamination theory (CLT). Then the simulation results were compared to the experimental results. In this study, conventional quasi-isotropic CFRP laminates and CFRP laminates which were stitched in the thickness direction were employed for the tests. Tensile tests and flexure tests were conducted. In the simulation, microscopic model which was consisted of solid elements and macroscopic model which was consisted of shell elements were both employed. Simulation results agreed very well with CLT results, and simulated results agreed with experimental results for both conventional and stitched CFRP plates.