Multiple genes for G protein-coupled receptors and their expression in lingual epithelia

Keiko Abe; Yuko Kusakabe; Kentaro Tanemura; Yasufumi Emori; Soichi Arai

doi:10.1016/0014-5793(93)81302-G

Multiple genes for G protein-coupled receptors and their expression in lingual epithelia

Keiko Abe, Yuko Kusakabe, Kentaro Tanemura, Yasufumi Emori, Soichi Arai

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

Using the polymerase chain reaction (PCR), we identified a gene family including more than 60 members which encoded similar G protein-coupled seven-transmembrane receptors. Sequence analyses of six representatives out of the 60 PCR clones showed that they had significant structural similarity to olfactory and optic receptors. Their expression is restricted in the surface of lingual epithelia.

Original language	English
Pages (from-to)	253-256
Number of pages	4
Journal	FEBS Letters
Volume	316
Issue number	3
DOIs	https://doi.org/10.1016/0014-5793(93)81302-G
Publication status	Published - 1993 Feb 1
Externally published	Yes

Keywords

G protein-coupled receptor
Lingual epithelium
Polymerase chain reaction
Taste receptor

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/0014-5793(93)81302-G

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abstract = "Using the polymerase chain reaction (PCR), we identified a gene family including more than 60 members which encoded similar G protein-coupled seven-transmembrane receptors. Sequence analyses of six representatives out of the 60 PCR clones showed that they had significant structural similarity to olfactory and optic receptors. Their expression is restricted in the surface of lingual epithelia.",

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AU - Abe, Keiko

AU - Kusakabe, Yuko

AU - Tanemura, Kentaro

AU - Emori, Yasufumi

AU - Arai, Soichi

PY - 1993/2/1

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AB - Using the polymerase chain reaction (PCR), we identified a gene family including more than 60 members which encoded similar G protein-coupled seven-transmembrane receptors. Sequence analyses of six representatives out of the 60 PCR clones showed that they had significant structural similarity to olfactory and optic receptors. Their expression is restricted in the surface of lingual epithelia.

KW - G protein-coupled receptor

KW - Lingual epithelium

KW - Polymerase chain reaction

KW - Taste receptor

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Multiple genes for G protein-coupled receptors and their expression in lingual epithelia

Abstract

Keywords

ASJC Scopus subject areas

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