Multiobjective design optimization of stent geometry with wall deformation for triangular and rectangular struts

Narendra Kurnia Putra, Pramudita Satria Palar, Hitomi Anzai, Koji Shimoyama, Makoto Ohta

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The stent geometrical design (e.g., inter-strut gap, length, and strut cross-section) is responsible for stent–vessel contact problems and changes in the blood flow. These changes are crucial for causing some intravascular abnormalities such as vessel wall injury and restenosis. Therefore, structural optimization of stent design is necessary to find the optimal stent geometry design. In this study, we performed a multiobjective stent optimization for minimization of average stress and low wall shear stress ratio while considering the wall deformation in 3D flow simulations of triangular and rectangular struts. Surrogate-based optimization with Kriging method and expected hypervolume improvement (EHVI) are performed to construct the surrogate model map and find the best configuration of inter-strut gap (G) and side length (SL). In light of the results, G-SL configurations of 2.81–0.39 and 3.00–0.43 mm are suggested as the best configuration for rectangular and triangular struts, respectively. Moreover, considering the surrogate model and flow pattern conditions, we concluded that triangular struts work better to improve the intravascular hemodynamics. [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)15-26
Number of pages12
JournalMedical and Biological Engineering and Computing
Volume57
Issue number1
DOIs
Publication statusPublished - 2019 Jan 1

Keywords

  • Computational simulation
  • Kriging surrogate method
  • Multiobjective optimization
  • Restenosis
  • Stent

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computer Science Applications

Fingerprint Dive into the research topics of 'Multiobjective design optimization of stent geometry with wall deformation for triangular and rectangular struts'. Together they form a unique fingerprint.

  • Cite this