Multifunctional nanoprobes for nanoscale chemical imaging and localized chemical delivery at surfaces and interfaces

Yasufumi Takahashi, Andrew I. Shevchuk, Pavel Novak, Yanjun Zhang, Neil Ebejer, Julie V. MacPherson, Patrick R. Unwin, Andrew J. Pollard, Debdulal Roy, Charles A. Clifford, Hitoshi Shiku, Tomokazu Matsue, David Klenerman, Yuri E. Korchev

Research output: Contribution to journalArticlepeer-review

188 Citations (Scopus)

Abstract

Double take: Double-barrel carbon nanoprobes with integrated distance control for simultaneous nanoscale electrochemical and ion conductance microscopy can be fabricated with a wide range of probe sizes in less than two minutes. The nanoprobes allow simultaneous noncontact topographical (left image) and electrochemical imaging (right) of living neurons, as well as localized K+ delivery and simultaneous neurotransmitter detection.

Original languageEnglish
Pages (from-to)9638-9642
Number of pages5
JournalAngewandte Chemie - International Edition
Volume50
Issue number41
DOIs
Publication statusPublished - 2011 Oct 4

Keywords

  • biosensors
  • living cell imaging
  • nanoelectrodes
  • scanning probe microscopy
  • surface analysis

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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