TY - JOUR
T1 - Multicentric reticulohistiocytosis in a child with sclerosing lesion of the leg
T2 - Immunohistopathologic studies and therapeutic trial with systemic cyclosporine
AU - Kuramoto, Yoko
AU - Iizawa, Osamu
AU - Aiba, Setsuya
AU - Makino, Yoshio
AU - Tagami, Hachiro
PY - 1989/1/1
Y1 - 1989/1/1
N2 - Multicentric reticulohistiocytosis affecting a 13-year-old boy induced a sclerosing change of the leg. The cellular infiltrate comprising activated T lymphocytes and macrophages and human lymphocyte antigen (HLA)-DR expression by keratinocytes in lesional skin all suggest the involvement of cellular immune reactions. We administered systemic cyclosporine but could not obtain a favorable effect without a concomitant low dosage of prednisone
AB - Multicentric reticulohistiocytosis affecting a 13-year-old boy induced a sclerosing change of the leg. The cellular infiltrate comprising activated T lymphocytes and macrophages and human lymphocyte antigen (HLA)-DR expression by keratinocytes in lesional skin all suggest the involvement of cellular immune reactions. We administered systemic cyclosporine but could not obtain a favorable effect without a concomitant low dosage of prednisone
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U2 - 10.1016/S0190-9622(89)70040-2
DO - 10.1016/S0190-9622(89)70040-2
M3 - Article
C2 - 2915077
AN - SCOPUS:0024528007
VL - 20
SP - 329
EP - 335
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 2
ER -