Multi-Well Sensor Platform Based on a Partially Etched Structure of a Light-Addressable Potentiometric Sensor

Hoang Anh Truong; Carl Frederik Werner; Ko ichiro Miyamoto; Tatsuo Yoshinobu

doi:10.1002/pssa.201800764

Multi-Well Sensor Platform Based on a Partially Etched Structure of a Light-Addressable Potentiometric Sensor

Hoang Anh Truong, Carl Frederik Werner, Ko ichiro Miyamoto, Tatsuo Yoshinobu

Research output: Contribution to journal › Article › peer-review

Abstract

A multi-well-structured light-addressable potentiometric sensor (LAPS) plate is developed for measuring a plurality of sample solutions on a single sensor plate. It is also capable of high-resolution chemical imaging inside the well structure. It can be applied, for example, to quantification of metabolic activities and imaging of biological samples incubated in the well structure. A minimum pattern size of 20 µm line is visualized and a wider frequency bandwidth of up to 200 kHz for the sensor signal is obtained in the well structure, which will be suitable for recording chemical images at a high-frame-rate.

Original language	English
Article number	1800764
Journal	Physica Status Solidi (A) Applications and Materials Science
Volume	216
Issue number	12
DOIs	https://doi.org/10.1002/pssa.201800764
Publication status	Published - 2019 Jun 19

Keywords

chemical imaging sensors
light-addressable potentiometric sensors
multi-well sensors
spatial resolution

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Surfaces and Interfaces
Surfaces, Coatings and Films
Electrical and Electronic Engineering
Materials Chemistry

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10.1002/pssa.201800764

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abstract = "A multi-well-structured light-addressable potentiometric sensor (LAPS) plate is developed for measuring a plurality of sample solutions on a single sensor plate. It is also capable of high-resolution chemical imaging inside the well structure. It can be applied, for example, to quantification of metabolic activities and imaging of biological samples incubated in the well structure. A minimum pattern size of 20 µm line is visualized and a wider frequency bandwidth of up to 200 kHz for the sensor signal is obtained in the well structure, which will be suitable for recording chemical images at a high-frame-rate.",

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