Multi-walled carbon nanotubes-based glucose biosensor prepared by a layer-by-layer technique

Jiadong Huang; Yu Yang; Haibin Shi; Zhao Song; Zixia Zhao; Jun Ichi Anzai; Tetsuo Osa; Qiang Chen

doi:10.1016/j.msec.2005.06.002

Multi-walled carbon nanotubes-based glucose biosensor prepared by a layer-by-layer technique

Jiadong Huang, Yu Yang, Haibin Shi, Zhao Song, Zixia Zhao, Jun Ichi Anzai, Tetsuo Osa, Qiang Chen

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

52 Citations (Scopus)

Abstract

The loading of multi-walled carbon nanotubes (MWNTs) and glucose oxidase (GOx) in the alternate layers of a glucose biosensor was first optimized based on a layer-by-layer construction on the surface of a graphite disk electrode. With the increasing of MWNTs/GOx layers, the response current to glucose was changed regularly and the response current reached a maximum value when the number of MWNTs/GOx layers was 6. Owing to a good electrical conductivity, strong adsorption and excellent bioconsistency of MWNTs, the (MWNTs/GOx) ₆ films-coated glucose biosensor had an excellent electrochemical properties. The response current of the (MWNTs/GOx)₆ films-coated biosensor to 3 × 10^{- 2} M glucose was 1.63 μA while the response time was only 6.7 s. The linear range and the lowest detectable concentration of this biosensor was 5 × 10^{- 4}∼1.5 × 10^{- 2} M and 0.9 × 10^{- 4} M, respectively.

Original language	English
Pages (from-to)	113-117
Number of pages	5
Journal	Materials Science and Engineering C
Volume	26
Issue number	1
DOIs	https://doi.org/10.1016/j.msec.2005.06.002
Publication status	Published - 2006 Jan

Keywords

Glucose biosensor
Glucose oxidase
Layer-by-layer technique
Multi-walled carbon nanotubes

ASJC Scopus subject areas

Materials Science(all)
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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10.1016/j.msec.2005.06.002

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title = "Multi-walled carbon nanotubes-based glucose biosensor prepared by a layer-by-layer technique",

abstract = "The loading of multi-walled carbon nanotubes (MWNTs) and glucose oxidase (GOx) in the alternate layers of a glucose biosensor was first optimized based on a layer-by-layer construction on the surface of a graphite disk electrode. With the increasing of MWNTs/GOx layers, the response current to glucose was changed regularly and the response current reached a maximum value when the number of MWNTs/GOx layers was 6. Owing to a good electrical conductivity, strong adsorption and excellent bioconsistency of MWNTs, the (MWNTs/GOx) 6 films-coated glucose biosensor had an excellent electrochemical properties. The response current of the (MWNTs/GOx)6 films-coated biosensor to 3 × 10- 2 M glucose was 1.63 μA while the response time was only 6.7 s. The linear range and the lowest detectable concentration of this biosensor was 5 × 10- 4∼1.5 × 10- 2 M and 0.9 × 10- 4 M, respectively.",

keywords = "Glucose biosensor, Glucose oxidase, Layer-by-layer technique, Multi-walled carbon nanotubes",

author = "Jiadong Huang and Yu Yang and Haibin Shi and Zhao Song and Zixia Zhao and Anzai, {Jun Ichi} and Tetsuo Osa and Qiang Chen",

note = "Funding Information: This work was supported by the National Natural Science Foundation of China (No. 90209054), the Natural Science Foundation of Tianjin (No. 033802711) and the Project 863 of China (No. 2002AA326060). ",

year = "2006",

month = jan,

doi = "10.1016/j.msec.2005.06.002",

language = "English",

volume = "26",

pages = "113--117",

journal = "Materials Science and Engineering C",

issn = "0928-4931",

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TY - JOUR

T1 - Multi-walled carbon nanotubes-based glucose biosensor prepared by a layer-by-layer technique

AU - Huang, Jiadong

AU - Yang, Yu

AU - Shi, Haibin

AU - Song, Zhao

AU - Zhao, Zixia

AU - Anzai, Jun Ichi

AU - Osa, Tetsuo

AU - Chen, Qiang

N1 - Funding Information: This work was supported by the National Natural Science Foundation of China (No. 90209054), the Natural Science Foundation of Tianjin (No. 033802711) and the Project 863 of China (No. 2002AA326060).

PY - 2006/1

Y1 - 2006/1

N2 - The loading of multi-walled carbon nanotubes (MWNTs) and glucose oxidase (GOx) in the alternate layers of a glucose biosensor was first optimized based on a layer-by-layer construction on the surface of a graphite disk electrode. With the increasing of MWNTs/GOx layers, the response current to glucose was changed regularly and the response current reached a maximum value when the number of MWNTs/GOx layers was 6. Owing to a good electrical conductivity, strong adsorption and excellent bioconsistency of MWNTs, the (MWNTs/GOx) 6 films-coated glucose biosensor had an excellent electrochemical properties. The response current of the (MWNTs/GOx)6 films-coated biosensor to 3 × 10- 2 M glucose was 1.63 μA while the response time was only 6.7 s. The linear range and the lowest detectable concentration of this biosensor was 5 × 10- 4∼1.5 × 10- 2 M and 0.9 × 10- 4 M, respectively.

AB - The loading of multi-walled carbon nanotubes (MWNTs) and glucose oxidase (GOx) in the alternate layers of a glucose biosensor was first optimized based on a layer-by-layer construction on the surface of a graphite disk electrode. With the increasing of MWNTs/GOx layers, the response current to glucose was changed regularly and the response current reached a maximum value when the number of MWNTs/GOx layers was 6. Owing to a good electrical conductivity, strong adsorption and excellent bioconsistency of MWNTs, the (MWNTs/GOx) 6 films-coated glucose biosensor had an excellent electrochemical properties. The response current of the (MWNTs/GOx)6 films-coated biosensor to 3 × 10- 2 M glucose was 1.63 μA while the response time was only 6.7 s. The linear range and the lowest detectable concentration of this biosensor was 5 × 10- 4∼1.5 × 10- 2 M and 0.9 × 10- 4 M, respectively.

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Multi-walled carbon nanotubes-based glucose biosensor prepared by a layer-by-layer technique

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