MRP5b/SMRP mRNA is highly expressed in metallothionein- deficient mouse liver

Toshihiro Suzuki, Mika Agui, Tadayasu Togawa, Akira Naganuma, Kazuto Nishio, Shinzo Tanabe

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

To investigate whether multidrug resistance protein 5 (MRP5) functions as a xenobiotic detoxification factor, we measured MRP mRNA expression levels in metallothionein (MT)-I, II knockout mouse, and the results showed that MRP5b/SMRP, a splicing variant of MRP5, was highly expressed in the liver of MT-I, -II null mice.

Original languageEnglish
Pages (from-to)524-526
Number of pages3
JournalJournal of Health Science
Volume49
Issue number6
DOIs
Publication statusPublished - 2003 Dec

Keywords

  • Metallothionein
  • Multidrug resistance protein
  • Multidrug resistance protein 5

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis

Fingerprint Dive into the research topics of 'MRP5b/SMRP mRNA is highly expressed in metallothionein- deficient mouse liver'. Together they form a unique fingerprint.

Cite this