MR imaging of pituitary adenomas with sphenoid sinus invasion: Characteristic MR findings indicating fibrosis

K. Ishii, H. Ikeda, S. Takahashi, K. Matsumoto, T. Ishibashi, S. Tazawa

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

We reviewed MR images obtained before and after the injection of Gd- DTPA in six patients with pituitary adenoma extending into the sphenoid sinus, and correlated the imaging and histological findings. The portion of each adenoma involving the sphenoid sinus and seller floor was less intense on both T1- and T2-weighted spin-echo images and Gd-enhanced images when compared with the sellar/suprasellar solid portion of the adenoma, which showed marked contrast enhancement. Histological examination of adenoma specimens taken from the sphenoid sinus demonstrated abundant collagen fibers between the adenoma cells, whereas tumor tissue from the suprasellar region showed no fibrotic change. We concluded that pituitary adenomas seem to have a tendency to develop fibrosis on extension into the sphenoid sinus.

Original languageEnglish
Pages (from-to)173-178
Number of pages6
JournalRadiation Medicine - Medical Imaging and Radiation Oncology
Volume14
Issue number4
Publication statusPublished - 1996
Externally publishedYes

Keywords

  • magnetic resonance imaging
  • pituitary adenoma
  • sphenoid sinus invasion

ASJC Scopus subject areas

  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Oncology

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