Molecular mechanism of angiogenesis transcription factors and their therapeutic relevance

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

Controlling angiogenesis, either positively or negatively, is considered to be useful for the treatment of various diseases. Angiogenesis primarily depends on the phenotypic changes of vascular endothelial cells (ECs). Various genes are expressed in ECs during angiogenesis, and thus, understanding of the transcriptional control of these genes in ECs is very important. This review focuses on transcription factors that may play important roles in angiogenesis. (C) 2000 Elsevier Science Inc.

Original languageEnglish
Pages (from-to)51-60
Number of pages10
JournalPharmacology and Therapeutics
Volume87
Issue number1
DOIs
Publication statusPublished - 2000 Jul 1
Externally publishedYes

Keywords

  • Angiogenesis
  • Endothelial cell
  • Transcription factor
  • Vasculogenesis

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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